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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1920 1
1921 2
1922 2
1923 3
1924 1
1925 2
1926 1
1927 2
1928 3
1929 4
1930 5
1932 3
1933 3
1934 1
1935 3
1936 5
1938 1
1939 1
1940 2
1941 1
1942 2
1943 2
1944 3
1945 2
1946 6
1947 3
1948 3
1949 4
1950 5
1951 2
1952 5
1953 6
1954 7
1955 2
1956 3
1957 4
1958 3
1959 11
1960 8
1961 14
1962 6
1963 12
1964 19
1965 19
1966 36
1967 62
1968 66
1969 90
1970 79
1971 78
1972 143
1973 110
1974 112
1975 361
1976 362
1977 348
1978 404
1979 437
1980 463
1981 600
1982 631
1983 828
1984 909
1985 964
1986 1109
1987 1105
1988 1143
1989 1372
1990 1462
1991 1584
1992 1606
1993 1698
1994 1848
1995 2022
1996 2068
1997 2305
1998 2355
1999 2641
2000 3044
2001 3331
2002 3679
2003 4299
2004 5335
2005 6312
2006 6930
2007 7239
2008 8182
2009 8934
2010 9946
2011 10920
2012 11995
2013 13211
2014 13880
2015 14818
2016 15569
2017 16593
2018 18342
2019 19937
2020 23259
2021 25710
2022 26854
2023 27773
2024 12503

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314,354 results

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Page 1
Effect of ivacaftor on CFTR forms with missense mutations associated with defects in protein processing or function.
Van Goor F, Yu H, Burton B, Hoffman BJ. Van Goor F, et al. J Cyst Fibros. 2014 Jan;13(1):29-36. doi: 10.1016/j.jcf.2013.06.008. Epub 2013 Jul 23. J Cyst Fibros. 2014. PMID: 23891399 Free article.
METHODS: The effect of ivacaftor on CFTR function was tested in electrophysiological studies using a panel of Fischer rat thyroid (FRT) cells expressing 54 missense CFTR mutations that cause defects in the amount or function of CFTR at the cell surface. RESULTS: Ivacaftor …
METHODS: The effect of ivacaftor on CFTR function was tested in electrophysiological studies using a panel of Fischer rat thyroid (FRT) cell …
Ion Channel Modulators in Cystic Fibrosis.
Gentzsch M, Mall MA. Gentzsch M, et al. Chest. 2018 Aug;154(2):383-393. doi: 10.1016/j.chest.2018.04.036. Epub 2018 May 8. Chest. 2018. PMID: 29750923 Free PMC article. Review.
CFTR functions as a cyclic adenosine monophosphate-dependent anion channel that transports chloride and bicarbonate across epithelial surfaces, and disruption of these ion transport processes plays a central role in the pathogenesis of CF. ...CFTR correctors are designed t …
CFTR functions as a cyclic adenosine monophosphate-dependent anion channel that transports chloride and bicarbonate across epithelial sur …
Mucosal immune tolerance at the ocular surface in health and disease.
Galletti JG, Guzmán M, Giordano MN. Galletti JG, et al. Immunology. 2017 Apr;150(4):397-407. doi: 10.1111/imm.12716. Epub 2017 Feb 20. Immunology. 2017. PMID: 28108991 Free PMC article. Review.
But to avoid unnecessary inflammation, the ocular surface's mucosal immune system must also discriminate between harmless and potentially dangerous antigens, a seemingly complicated task. Despite its unique features, the ocular surface is a mucosal lin …
But to avoid unnecessary inflammation, the ocular surface's mucosal immune system must also discriminate between harmless and …
[Revolution in the treatment of cystic fibrosis].
Sauty A, Plojoux J, Mornand A, Blanchon S, Koutsokera A. Sauty A, et al. Rev Med Suisse. 2020 Jun 17;16(698):1229-1235. Rev Med Suisse. 2020. PMID: 32558451 Review. French.
Cystic Fibrosis is a genetic disorder resulting in the absence or dysfunction of the CFTR protein, a chloride channel present on the surface of epithelia, particularly respiratory. Until recently, treatments only concerned the consequences of the disease. ...An oral triple …
Cystic Fibrosis is a genetic disorder resulting in the absence or dysfunction of the CFTR protein, a chloride channel present on the surf …
S-Layer Protein-Based Biosensors.
Schuster B. Schuster B. Biosensors (Basel). 2018 Apr 11;8(2):40. doi: 10.3390/bios8020040. Biosensors (Basel). 2018. PMID: 29641511 Free PMC article.
The present paper highlights the application of bacterial surface (S-) layer proteins as versatile components for the fabrication of biosensors. ...The present paper discusses and summarizes examples for the successful implementation of S-layer lattices on biosensor …
The present paper highlights the application of bacterial surface (S-) layer proteins as versatile components for the fabricat …
Microplicae--Specialized Surface Structure of Epithelial Cells of Wet-Surfaced Oral Mucosa.
Asikainen P, Sirviö E, Mikkonen JJ, Singh SP, Schulten EA, ten Bruggenkate CM, Koistinen AP, Kullaa AM. Asikainen P, et al. Ultrastruct Pathol. 2015;39(5):299-305. doi: 10.3109/01913123.2015.1054015. Epub 2015 Jul 27. Ultrastruct Pathol. 2015. PMID: 26214246 Review.
The surface structure of the superficial cells of the oral mucosa is decorated with numerous membrane ridges, termed microplicae (MPLs). ...The interaction between MPLs and the mucins has been demonstrated, however the role of MPL structure seen on the upper surface …
The surface structure of the superficial cells of the oral mucosa is decorated with numerous membrane ridges, termed microplicae (MPL …
Exosomal therapy-a new frontier in regenerative medicine.
Muthu S, Bapat A, Jain R, Jeyaraman N, Jeyaraman M. Muthu S, et al. Stem Cell Investig. 2021 Apr 2;8:7. doi: 10.21037/sci-2020-037. eCollection 2021. Stem Cell Investig. 2021. PMID: 33969112 Free PMC article. Review.
Various in vitro studies have exhibited the safety, efficacy, and therapeutic potentiality of exosomes in various cancers, neurodegenerative, cardiovascular, and orthopedic diseases. This article throws light on the composition, therapeutic role, and regulatory potentia …
Various in vitro studies have exhibited the safety, efficacy, and therapeutic potentiality of exosomes in various cancers, neurodegen …
Current development of CFTR potentiators in the last decade.
Spanò V, Venturini A, Genovese M, Barreca M, Raimondi MV, Montalbano A, Galietta LJV, Barraja P. Spanò V, et al. Eur J Med Chem. 2020 Oct 15;204:112631. doi: 10.1016/j.ejmech.2020.112631. Epub 2020 Jul 15. Eur J Med Chem. 2020. PMID: 32898816 Review.
Cystic fibrosis (CF) is a genetic disorder produced by the loss of function of CFTR, a main chloride channel involved in transepithelial salt and water transport. CFTR function can be rescued by small molecules called "potentiators" which increase gating activity of CFTR o …
Cystic fibrosis (CF) is a genetic disorder produced by the loss of function of CFTR, a main chloride channel involved in transepithelial sal …
Poly(N-isopropylacrylamide) Hydrogel for Diving/Surfacing Device.
Choi JG, Gwac H, Jang Y, Richards C, Warren H, Spinks G, Kim SJ. Choi JG, et al. Micromachines (Basel). 2021 Feb 19;12(2):210. doi: 10.3390/mi12020210. Micromachines (Basel). 2021. PMID: 33669511 Free PMC article.
The gel surfaced in water when heated and sank when cooled. We further showed reversible diving/surfacing cycles of the device when exposed to electrical and ultrasonic stimuli. ...These results suggest that the poly(N-isopropylacrylamide)-containing device has good …
The gel surfaced in water when heated and sank when cooled. We further showed reversible diving/surfacing cycles of the device …
Surface treatments for controlling corrosion rate of biodegradable Mg and Mg-based alloy implants.
Uddin MS, Hall C, Murphy P. Uddin MS, et al. Sci Technol Adv Mater. 2015 Sep 8;16(5):053501. doi: 10.1088/1468-6996/16/5/053501. eCollection 2015 Oct. Sci Technol Adv Mater. 2015. PMID: 27877829 Free PMC article. Review.
This article presents a comprehensive review of recent research focusing on surface treatment techniques utilised to control the corrosion rate and surface integrity of Mg-based alloys in both in vitro and in vivo environments. Surface treatments generally in …
This article presents a comprehensive review of recent research focusing on surface treatment techniques utilised to control the corr …
314,354 results
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